After having called his disciples Jesus started his Messianic work: preaching and healing. Evening came (1:32) and morning came (1:35), a new day. That new day brought new things. Jesus went to other towns to proclaim the Good News (1:38-39). And another aspect of the new day was that his Messianic work had adverse effects for him. We haven’t previously heard that in the gospels. In this case he touched a leper and had to isolate himself in the desert.
Source: Jesuits in Britain